yogabook / pathologie / psoriasis

Psoriasis (psoriasis, scabies, mange)

Definition of

Benign, hereditary disposition disease of the skin, fingernails and joints, also in the form of arthritis; polygenic inheritance, multifactorial onset, usually in the 2nd year of life, often after febrile infections, also after the 50th year of life without familial disposition. Predominantly light-skinned people, approx. 1-2% of Europeans. Note: Psoriasis is a false reaction of the skin to trauma (physical, chemical, inflammatory) with over-supported epidermis formation (keratocyte migration time 4 instead of 28 days).

ICD L40

Predisposing

1. Gravidity
2. Stress
3. HIV infection
4. best. Medication

Diagnosis

1. Laboratory: HLA-B27, HLA-BW17 or HLA-CW6 in the blood
2. Laboratory: higher uric acid level(risk of gout)

Symptoms

1. Foci appear on relatively high-stress areas of the body (elbows, knees), where the mitosis rate is increased by up to a factor of 5, leading to abnormal keratinization. Predilection sites are the extensor sides of the extremities, the transition to the hairy head area and the sacral region. There are also patients with disseminated distribution: from isolated small patches to completely widespread. Psoriasis begins with sharply defined inflammatory papules with small silvery-white scales that flake off easily. The papules are not painful. Psoriasis causes hardly any pain and little itching except when irritated! Unfortunately, irritation is often caused by clothing. The scales are waxy and greasy, very small, bran-like; scraped areas are red, smooth, shiny. The skin underneath may be slightly bruised, possibly a small drop of blood may appear (bloody dew, exfoliation phenomenon). It does not ooze.
2. On the nails:
   1. Stippled nails: funnel-shaped indentations in the nail surface, small holes
   2. Oil spots: yellowish-brownish color changes/spots in the nail plate
   3. Nail dystrophies: crooked nails
3. Symptoms in the joints: arthritis in the area of the small joints, especially the fingers
4. Non-visible changes: patients have an increased risk of heart attack, apoplexy, pulmonary embolism, as they have an increased cholesterol level and an increased tendency to thrombi and are more likely to develop arteriosclerosis

Complications

1. Heart attack
2. Apoplexy
3. Pulmonary embolism
4. Gout
5. Joint infestation (psoriatic arthritis)

Therapy

1. Remove dandruff with salicylic acid, followed by „PUVA“: the petroleum-derived drug psoralen (quite smelly) plus UV-A radiation